Japan’s Nikkei slips from 33-year high as investors book profits

Japan’s Nikkei share average fell on Tuesday as investors exited some bullish positions after the benchmark index closed at a 33-year high in the previous session. A market holiday in the U.S. added to the cautious mood.

The Nikkei fell 1.08% to 33,389.28 by the midday break, after ending at 33,753.33, its highest close since March 1990, on Monday.

Drugmaker Daiichi Sankyo tumbled more than 14% to lead Nikkei decliners by a wide margin, after a trial of an experimental cancer drug developed with AstraZeneca disappointed investors.

Every Nikkei sector but one declined, led by a 3.37% slide for healthcare. Financials, however, added 0.88% tracking gains in U.S. peers overnight, as they raised dividends after sailing through annual stress tests.

Japan’s broader Topix index declined 0.72% to 2,304.03.

“In terms of the Nikkei’s decline today, with U.S. markets on holiday, it’s hard to expect investors to proactively take on new positions,” said Maki Sawada, a strategist at Nomura Securities.

“Considering too that the Nikkei closed at a new high yesterday, profit-taking selling is leading today’s market moves.”

Robot maker Fanuc fell 2.82% to be the Nikkei’s biggest decliner after Daiichi Sankyo. Home appliance maker Daikin Industries followed with a 2.75% slide.

Other notable losers included Uniqlo store operator Fast Retailing, down 1.46%, and startup investor SoftBank Group, which fell 0.89%.

At the other end, online retailer Rakuten Group led Nikkei gainers with a 5.63% surge, continuing its rebound from a 14-year low hit last week.

Resona Holdings was the top performing bank, rallying 2.81%. Mizuho Financial Group rose 2.63%.

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